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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065171Generated: October 26, 2026

2-Chlorocinnamic acid → (E)-3-(2-Chloro-phenyl)-N-[1-(5-oxo-hexyl)-1H-pyrazol-4-yl]-acrylamide

https://huagongshe.com/reaction/2065171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chlorocinnamic acidHCID 700642—
Reactant1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamineHCID 66928726—
Product(E)-3-(2-Chloro-phenyl)-N-[1-(5-oxo-hexyl)-1H-pyrazol-4-yl]-acrylamideHCID 66928253—

Reaction Steps

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamine and (E)-3-(2-chloro-phenyl)-acrylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-f9d3d740202c4aa1be13ea9054a00574
Source noteuspto-grants-2012_10