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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065212Generated: October 26, 2026

2-Chlorocinnamic acid → (E)-3-(2-Chloro-phenyl)-N-[1-(5,5-difluoro-hexyl)-1H-pyrazol-3-yl]-acrylamide

https://huagongshe.com/reaction/2065212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chlorocinnamic acidHCID 700642—
Reactant1-(5,5-Difluoro-hexyl)-1H-pyrazol-3-ylamineHCID 66928304—
Product(E)-3-(2-Chloro-phenyl)-N-[1-(5,5-difluoro-hexyl)-1H-pyrazol-3-yl]-acrylamideHCID 66929356—

Reaction Steps

Following general procedure B, starting from 1-(5,5-difluoro-hexyl)-1H-pyrazol-3-ylamine and (E)-3-(2-chloro-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.13 min; [M+H]+=368.25.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-700e6b41963747388c150d5f92c29b5d
Source noteuspto-grants-2012_10