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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065242Generated: October 25, 2026

2',3'-Dimethoxycinnamic acid → (E)-N-{1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-yl}-3-(2,3-dimethoxy-phenyl)-acrylamide

https://huagongshe.com/reaction/2065242

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2',3'-Dimethoxycinnamic acidHCID 735842—
Reactant1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamineHCID 66929369—
Product(E)-N-{1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-yl}-3-(2,3-dimethoxy-phenyl)-acrylamideHCID 66929290—

Reaction Steps

Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-(2,3-dimethoxy-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.09 min; [M+H]+=418.09.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-60bbc2883e49426aa7dff7d72c68aff3
Source noteuspto-grants-2012_10