HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propenoic acid, 3-(3-chlorophenyl)- → (E)-3-(3-Chloro-phenyl)-N-{1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-yl}-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propenoic acid, 3-(3-chlorophenyl)- | HCID 735250 | — |
| Reactant | 1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine | HCID 66929369 | — |
| Product | (E)-3-(3-Chloro-phenyl)-N-{1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-yl}-acrylamide | HCID 66928427 | — |
Reaction Steps
Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-(3-chloro-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.14 min; [M+H]+=392.14.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-51b29225ec9140b58e4e4a4fea3da88d |
| Source note | uspto-grants-2012_10 |