HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Chlorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → 5-(4-Chloro-phenyl)-2-methyl-thiazole-4-carboxylic acid [1-(5-acetyl-thiophen-2-ylmethyl)-1H-pyrazol-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Chlorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid | HCID 23146317 | — |
| Reactant | HCID 66928512 | HCID 66928512 | — |
| Product | 5-(4-Chloro-phenyl)-2-methyl-thiazole-4-carboxylic acid [1-(5-acetyl-thiophen-2-ylmethyl)-1H-pyrazol-4-yl]-amide | HCID 66928392 | — |
Reaction Steps
Following general procedure X followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(4-chloro-phenyl)-2-methyl-thiazole-4-carboxylic acid. LC-MS-conditions 05c: tR=0.77 min; [M+H]+=457.15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-0ab72f42763645d4a529b50802ead108 |
| Source note | uspto-grants-2012_10 |