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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065347Generated: October 30, 2026

1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine → 5-(6-Trifluoromethyl-pyridin-2-yl)-oxazole-4-carboxylic acid [1-(5-acetyl-furan-2-ylmethyl)-1H-pyrazol-4-yl]-amide

https://huagongshe.com/reaction/2065347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66928611—
ReactantHCID 66928955HCID 66928955—
Product5-(6-Trifluoromethyl-pyridin-2-yl)-oxazole-4-carboxylic acid [1-(5-acetyl-furan-2-ylmethyl)-1H-pyrazol-4-yl]-amideHCID 66928343—

Reaction Steps

Following general procedure Z3 followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(6-trifluoromethyl-pyridin-2-yl)-oxazole-4-carboxylic acid lithium salt. LC-MS-conditions 02: tR=0.92 min; [M+H]+=446.24.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-291e4d48ea414ee08561169b045c21a2
Source noteuspto-grants-2012_10