Ornithine hydrochloride → HCID 45255157, compound
Reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[CH2:16]([CH2:23][NH2:24])[CH2:17][C@H:18]([NH2:22])[C:19]([OH:21])=[O:20].[ClH:25]>>[C:19]([C@@H:18]([NH:22][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:25])[CH:8]=2)[N:3]=1)[CH2:17][CH2:16][CH2:23][NH:24][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)([OH:21])=[O:20]Participants
3
Procedure
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with L-2,5-diaminopentanoic acid to provide the title compound in good yield.
Sources & evidence
- ORD record
- ord-a9a3388168b64c2b86e179d47eed7831
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08288549B2
Reaction notes
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