Dl-Phenylalanine → HCID 45255377, compound

HRID 2065637Notes

Reaction equation

HRID 2065637 reaction equation
C([O:3][C:4]([C:6]1[C:7](Cl)=[N:8][C:9]2[C:14]([CH:15]=1)=[CH:13][C:12]([Br:16])=[CH:11][C:10]=2[Br:17])=[O:5])C.[NH2:19][CH:20]([C:28]([OH:30])=[O:29])[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Br:16][C:12]1[CH:13]=[C:14]2[C:9](=[C:10]([Br:17])[CH:11]=1)[N:8]=[C:7]([NH:19][CH:20]([C:28]([OH:30])=[O:29])[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:6]([C:4]([OH:3])=[O:5])=[CH:15]2

Participants

3

Reactant 2

HCID 994Dl-PhenylalanineHCID 86656381HCID 86656381, compound

Product 1

HCID 45255377HCID 45255377, compound

Procedure

In close analogy to the procedure described in Example 32, 6,8-dibromo-2-chloro-quinoline-3-carboxylic acid ethyl ester is reacted with DL-phenylalanine to provide the title compound in good yield.

Sources & evidence

ORD record
ord-3ae2b88167f749e69610a05ed209400f
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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