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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065670Generated: October 30, 2026

2,6-Dichloroquinoline-3-carboxylic acid → HCID 45256528, compound

https://huagongshe.com/reaction/2065670

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dichloroquinoline-3-carboxylic acidHCID 24266068—
ReactantHCID 67360295HCID 67360295—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 45256528HCID 45256528—

Reaction Steps

In close analogy to the procedure described in Example 32; 2,6-dichloro-quinoline-3-carboxylic acid is reacted with (S)-2-amino-3-[4-(5-bromo-pyridin-2-yloxy)-phenyl]-propionic acid in DMSO to provide the title compound in good yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288549B2
Source datasetuspto-grants-2012_10
ORD IDord-f18f6181a7b04ecba9ea20cc705a781a
Source noteuspto-grants-2012_10