HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloroquinoline-3-carboxylic acid → HCID 178524039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Reactant | HCID 178511767 | HCID 178511767 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178524039 | HCID 178524039 | — |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with (S)-2-amino-3-phenyl-N-(1H-tetrazol-5-yl)-propionamide (prepared by reaction of N-Boc-L-phenylalanine with isobutyl chloroformate followed by 5-amino-1H-tetrazole) in DMSO to provide the title compound in moderate yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-a4bc8ab4791e4cfc856a2606216068ca |
| Source note | uspto-grants-2012_10 |