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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065759Generated: October 31, 2026

1,4-Dibenzylpiperazine-2-carboxylic acid → 1-(2,5-Xylyl)piperazine

https://huagongshe.com/reaction/2065759

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dibenzylpiperazine-2-carboxylic acidHCID 22324245—
Reactant(1,4-Dibenzyl-piperazin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanoneHCID 68729979—
Product1-(2,5-Xylyl)piperazineHCID 70542—

Reaction Steps

In analogy to example 1, step 1, from 1,4-dibenzylpiperazine-2-carboxylic acid (CAS Reg. No.: [215597-67-4]) and 1-(2,5-dimethylphenyl)piperazine was prepared (1,4-dibenzyl-piperazin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanone as a white foam, MS: 483.3 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288541B2
Source datasetuspto-grants-2012_10
ORD IDord-958fa825890845b0bd959159d9a7b3a1
Source noteuspto-grants-2012_10