Sodium ion → 5-(4-Fluorophenyl)-7-isopropyl-6-[4-(trifluoromethoxy)benzoyl]spiro[chromen-2,1'-cyclobutan]-4(3H)-one
Reaction equation
[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl:1][CH2:2][Cl:3].[F:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[c:18]3[c:23]([cH:24][c:25]([CH:40]([CH3:41])[CH3:42])[c:26]2[CH:27]([c:28]2[cH:29][cH:30][c:31]([O:34][C:35]([F:36])([F:37])[F:38])[cH:32][cH:33]2)[OH:39])[O:22][C:21]2([CH2:20][C:19]3=[O:46])[CH2:43][CH2:44][CH2:45]2)[cH:15][cH:16]1.[Na+:54].[OH-:53].[cH:4]1[cH:5][cH:6][n:7][cH:8][cH:9]1>>[F:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[c:18]3[c:23]([cH:24][c:25]([CH:40]([CH3:41])[CH3:42])[c:26]2[C:27]([c:28]2[cH:29][cH:30][c:31]([O:34][C:35]([F:36])([F:37])[F:38])[cH:32][cH:33]2)=[O:39])[O:22][C:21]2([CH2:20][C:19]3=[O:46])[CH2:43][CH2:44][CH2:45]2)[cH:15][cH:16]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-dc48412641144a5bab4e9a235dce0a26
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…