HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nicotinic Acid → 6-(2-Methylpropyl)pyridine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nicotinic Acid | HCID 938 | — |
| Reactant | Ethyl 6-chloronicotinate | HCID 2799611 | — |
| Reactant | HCID 178418368 | HCID 178418368 | — |
| Product | 6-(2-Methylpropyl)pyridine-3-carboxylic acid | HCID 19865917 | — |
Reaction Steps
6-Isobutyl-nicotinic acid is prepared in analogy to Nicotinic acid 2 from commercially available 6-chloronicotinic acid ethyl ester and isobutylmagnesium chloride; LC-MS: tR=0.52 min, [M+1]+=180.30.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288554B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-29915a030c91465a86dfcd448c948a33 |
| Source note | uspto-grants-2012_10 |