HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (2S,3aR,7aS)-Ethyl octahydro-1H-indole-2-carboxylate | HCID 33789390 | — |
| Product | (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride | HCID 24820572 | — |
Reaction Steps
6 N hydrochloric acid (6 mL) was added to 0.42 g of (2S,3aR,7aS)-ethyl octahydro-1H-indole-2-carboxylate (16) and heated to reflux for NLT 4 hours. The mixture was concentrated and dried under vacuum to afford 0.42 g of (2S,3aR,7aS)-octahydro-1H-indole-2-carboxylic acid hydrochloride (5) as a crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288565B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-861673033fe34074946ba5028973f40e |
| Source note | uspto-grants-2012_10 |