2-Methylpiperazine → (RS)-1-cyclopropyl-3-ethoxycarbonyl-7,9-difluoro-8-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine

HRID 206614Notes

Reaction equation

HRID 206614 reaction equation
[CH3:27][CH:28]1[NH:29][CH2:30][CH2:31][NH:32][CH2:33]1.[CH:1]1([n:4]2[cH:5][c:6]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:7](=[O:21])[c:8]3[cH:9][c:10]4[c:11]([n:12][c:13]23)[c:14]([F:20])[c:15]([F:19])[c:16]([F:18])[cH:17]4)[CH2:2][CH2:3]1>>[CH:1]1([n:4]2[cH:5][c:6]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:7](=[O:21])[c:8]3[cH:9][c:10]4[c:11]([n:12][c:13]23)[c:14]([F:20])[c:15]([N:32]2[CH2:31][CH2:30][NH:29][CH:28]([CH3:27])[CH2:33]2)[c:16]([F:18])[cH:17]4)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 660572-MethylpiperazineHCID 185491641-Cyclopropyl-3-ethoxycarbonyl-7,8,9-trifluoro-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine

Product 1

HCID 20063285(RS)-1-cyclopropyl-3-ethoxycarbonyl-7,9-difluoro-8-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine

Sources & evidence

ORD record
ord-84d6f827a37c49ff8d918213c5991bc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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