Glycerol → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

HRID 2066360Notes

Reaction equation

[OH-:1].[K+].[OH:3][CH2:4][CH:5]([CH2:7][OH:8])[OH:6]>>[O:3]=[CH:4][C@@H:5]([C@H:7]([C@@H:7]([C@@H:5]([CH2:4][OH:3])[OH:6])[OH:1])[OH:8])[OH:6]

Participants

Reactant 2

HCID 753Glycerol

HCID 14797Potassium Hydroxide

Product 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Procedure

The medium was adjusted to pH 7.0 with KOH, autoclaved at 115° C. for 10 minutes (provided that glycerol or glucose and MgSO4.7H2O were separately sterilized) and then 30 g/L of CaCO3 defined in Japanese Pharmacopoeia (subjected to hot air sterilization at 180° C. for 2 hours) was added.

Sources & evidence

ORD record: ord-f43ae54d7e6048b2a6b1625477d74b91
Source dataset: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08293505B2

Reaction notes

Loading…