HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxyacetophenone → 3-[1-Hydroxy-1-(3-methylphenyl)ethyl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxyacetophenone | HCID 8487 | — |
| Reactant | HCID 178425419 | HCID 178425419 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-[1-Hydroxy-1-(3-methylphenyl)ethyl]phenol | HCID 67387546 | — |
Reaction Steps
By using 3′-hydroxyacetophenone (200 mg) and a 1 M solution of m-tolylmagnesium chloride in tetrahydrofuran (4.4 ml) as starting materials, the title compound (329.0 mg) was obtained in the same manner as that of Reference Example 69.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293715B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-5c2c6b537f004105b562a6d65d56be2d |
| Source note | uspto-grants-2012_10 |