HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 66995212, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 123929593 | HCID 123929593 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66995212 | HCID 66995212 | — |
Reaction Steps
A solution of Example 31A (0.17 g, 0.319 mmol) in CH2Cl2 (4 mL) under argon was treated with trifluoroacetic acid (1 ml, 12.98 mmol), stirred at room temperature for 1 hour, then partitioned between dilute Na2CO3 solution and ethyl acetate (2×). The combined organics were dried (MgSO4), then concentrated to afford the title compound which was used as is in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293738B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-bdbfc527125b4bb7aaf422c9b6d920c4 |
| Source note | uspto-grants-2012_10 |