(3aR,7aS)-rel-tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate → 5-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester

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Prepared according to the method used in the preparation of 8-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-1,4-dioxa-8-aza-spiro[4.5]decane using octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester in place of 1,4-dioxa-8-aza-spiro[4.5]decane. The title compound was obtained as white solid (153 mg, 90%).

Provenance & Evidence