HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58117100, compound → (+/-)-[(trans)-4-Azetidin-1-yl-1-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperidin-3-yl]-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58117100 | HCID 58117100 | — |
| Reactant | (4-Azetidin-1-yl-piperidin-3-yl)-methanol | HCID 66870060 | — |
| Product | (+/-)-[(trans)-4-Azetidin-1-yl-1-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperidin-3-yl]-methanol | HCID 86761639 | — |
Reaction Steps
Prepared according to the method used in the preparation of 2-chloro-6-(7-methyl-2,7-diaza-spiro[3.5]non-2-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine using (4-azetidin-1-yl-piperidin-3-yl)-methanol in place of 7-methyl-2,7-diaza-spiro[3.5]nonane. The title compounds were separated by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293735B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-45f384b338804d80a4739e938bf6d204 |
| Source note | uspto-grants-2012_10 |