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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2066534Generated: October 31, 2026

(S)-octahydropyrazino[2,1-c][1,4]oxazine → HCID 58117122, compound

https://huagongshe.com/reaction/2066534

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-octahydropyrazino[2,1-c][1,4]oxazineHCID 59452751—
ReactantHCID 86650185HCID 86650185—
ProductHCID 58117122HCID 58117122—

Reaction Steps

Prepared according to the method used in the preparation of (S)-4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-3-isopropyl-piperazin-2-one using (5)-octahydro-pyrazino[2,1-c][1,4]oxazine in place of (S)-3-isopropyl-piperazin-2-one. The title compound was obtained as a pale yellow solid (210 mg, 90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293735B2
Source datasetuspto-grants-2012_10
ORD IDord-16e66475e5d14609b347459ca17a1d14
Source noteuspto-grants-2012_10