HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Oxan-4-yl)piperazine → HCID 58117126, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Oxan-4-yl)piperazine | HCID 21942315 | — |
| Reactant | 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde | HCID 45789985 | — |
| Product | HCID 58117126 | HCID 58117126 | — |
Reaction Steps
Prepared from 1-(tetrahydro-pyran-4-yl)-piperazine and 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde under reductive amination conditions described in Reference Example 39, to give, after silica chromatography purification, the title compound as a white solid (190 mg, 61%) [M+H]+ 439.4
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293735B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-7db005d6b2a04145a3b645c6aee4dba0 |
| Source note | uspto-grants-2012_10 |