HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58117149, compound → HCID 46238784, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58117149 | HCID 58117149 | — |
| Reactant | 1H-Indole-6-carbonitrile, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- | HCID 66882064 | — |
| Product | HCID 46238784 | HCID 46238784 | 21.7% |
Reaction Steps
A mixture of 2-chloro-6-(4-cyclopropyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (200 mg) and 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-H-indole-6-carbonitrile (273 mg) were reacted using Suzuki coupling method B, to give the title compound (55 mg) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293735B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-544c0becff8145d2be1761e0e0c7d5eb |
| Source note | uspto-grants-2012_10 |