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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2066790Generated: November 2, 2026

HCID 66851478, compound → HCID 66890967, compound

https://huagongshe.com/reaction/2066790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66851478HCID 66851478—
CatalystPalladiumHCID 23938—
SolventWaterHCID 962—
ProductHCID 66890967HCID 66890967—

Reaction Steps

The title compound was prepared in analogy to the procedure described in Step 1.8 but (2S,3S)-3-(acetylamino-methyl)-1-((S)-1-phenyl-ethyl)-pyrrolidine-2-carboxylic acid amide (Step 5.2) was used instead of (2S,3R)-3-methyl-1-((S)-1-phenyl-ethyl)-pyrrolidine-2-carboxylic acid amide. Moreover, 10% Pd on charcoal, wet with 50% H2O (Aldrich 330108) was used instead of the dry catalyst.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293753B2
Source datasetuspto-grants-2012_10
ORD IDord-64498bd18a5c48b58ad0a7b3a213c2f1
Source noteuspto-grants-2012_10