HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrrolo(2,3-b)pyridine → HCID 69081056, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrrolo(2,3-b)pyridine | HCID 9222 | — |
| Reactant | 4-Bromoisoquinoline | HCID 73743 | — |
| Reactant | HCID 86633779 | HCID 86633779 | — |
| Product | HCID 69081056 | HCID 69081056 | 61% |
Reaction Steps
2(benzylsulfonyl-1-(7-aza-1H-indol-3-yl)-4-bromo-1,2-dihydroisoquinoline: Following the procedure of Example 1, 29.54 mg (0.25 mmol) of 7-azaindole was treated with 104.03 mg (0.5 mmole) of 4-bromoisoquinoline and 47.67 mg (0.25 mmol) of α-phenylmethylsulphonyl chloride to yield 71.98 mg (61% Yield) of 2(benzylsulfonyl)-1-(7-aza-1H-indol-3-yl)-4-bromo-1,2-dihydroisoquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293764B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-2c06804112a740ad98b6f29da2a7b554 |
| Source note | uspto-grants-2012_10 |