2-azido-acetamide → HCID 86605522, compound

HRID 2067201Notes

Reaction equation

HRID 2067201 reaction equation
[N:1]([CH2:4][C:5](N)=O)=[N+:2]=[N-:3].ClCC[CH2:11][S:12]([NH2:15])(=[O:14])=[O:13]>>[N:1]([CH2:4][CH2:5][CH2:11][S:12]([NH2:15])(=[O:14])=[O:13])=[N+:2]=[N-:3]

Participants

3

Reactant 2

HCID 32462232-azido-acetamideHCID 136148183-Chloropropane-1-sulfonamide

Product 1

HCID 86605522HCID 86605522, compound

Procedure

The reaction was carried out similarly as described in the preparation of compound 411, using compound 3-chloro-propane-1-sulfonic acid amide (19.0 mmol). The crude product was purified by continuous gradient flash chromatography using EtOAc/petroleum ether (40-60) 35:65 to 65:35 as the eluent to afford the title compound as colourless oil.

Workup

  1. customThe crude product was purified by continuous gradient flash chromatography

Sources & evidence

ORD record
ord-60ba2f2e123d4fbaa3beccc533e74e73
Source dataset
uspto-grants-2012_10
Patent number
US08293772B2

Reaction notes

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