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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2067214Generated: November 3, 2026

(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanone → (5-Amino-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanone

https://huagongshe.com/reaction/2067214

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanoneHCID 68419668—
Reactant[2-Chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-(2-methyl-5-nitro-phenyl)-methanoneHCID 68421804—
Product(5-Amino-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanoneHCID 68417005—

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 415, using compound 420 (0.21 mmol). The crude product was used without any further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293772B2
Source datasetuspto-grants-2012_10
ORD IDord-337986a815d34ef688e20f3f85fbbdee
Source noteuspto-grants-2012_10