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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2067215Generated: November 2, 2026

(5-Amino-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanone → (5-Azido-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanone

https://huagongshe.com/reaction/2067215

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Amino-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanoneHCID 68417005—
Reactant(5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanoneHCID 86605524—
Product(5-Azido-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanoneHCID 86605525—

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 416, using compound 421 (0.21 mmol). The crude product was used without any further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293772B2
Source datasetuspto-grants-2012_10
ORD IDord-f2771d981c9c4f2eaf61a1aba756376d
Source noteuspto-grants-2012_10