反应详情

The reaction was carried out similarly as described in the preparation of compound 403, using compound 402 (22.6 mmol) and 4-fluoroaniline (24.8 mmol) except the time for the reaction was 16 h. The crude product was purified by flash chromatography using EtOAc/petroleum ether (40-60) 1:5 as the eluent to afford the title compound as yellow solid.

1. customThe crude product was purified by flash chromatography