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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2067251Generated: November 1, 2026

(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl]-methanone → (5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl]-methanone

https://huagongshe.com/reaction/2067251

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl]-methanoneHCID 68418968—
Reactant(5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanoneHCID 86605524—
Product(5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl]-methanoneHCID 86605531—

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 416, using compound 438 (0.29 mmol). The crude product was used without any further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293772B2
Source datasetuspto-grants-2012_10
ORD IDord-ee2616a6216a482f93ca6b70e34dcb90
Source noteuspto-grants-2012_10