HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2068007Generated: October 31, 2026
Hydrochloric Acid → HCID 131730039, compound
https://huagongshe.com/reaction/2068007
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 87536609 | HCID 87536609 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 131730039 | HCID 131730039 | — |
Reaction Steps
To a solution of tert-butyl 4-(propylsulfonylmethyl)thiazol-2-ylcarbamate (16 mmol) in 1,4-dioxane (25 mL) was added 4N HCl in 1,4-dioxane (300 mL) and was stirred for 4 hours at 40° C. Removal of the volatiles afforded 4-(propylsulfonylmethyl)thiazol-2-amine HCl-salt (3.99 g, quant. yield) as a crème-colored solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08293919B2 |
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| Source dataset | uspto-grants-2012_10 |
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| ORD ID | ord-b20fa92b85c040bbb1ede74fbd35efb8 |
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| Source note | uspto-grants-2012_10 |
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