HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl octahydro-5H-pyrrolo(3,4-c)pyridine-5-carboxylate → tert-butyl 2-(3-(3-(trifluoromethoxy)phenylsulfonyl)quinolin-8-yl)hexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl octahydro-5H-pyrrolo(3,4-c)pyridine-5-carboxylate | HCID 19691292 | — |
| Reactant | 8-Iodo-3-(3-(trifluoromethoxy)phenylsulfonyl)quinoline | HCID 68729086 | — |
| Product | tert-butyl 2-(3-(3-(trifluoromethoxy)phenylsulfonyl)quinolin-8-yl)hexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate | HCID 25196511 | 54% |
Reaction Steps
The title compound was prepared by analogy to the procedure of Example 1.3, except using tert-butyl hexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate and 8-iodo-3-(3-(trifluoromethoxy)phenylsulfonyl)quinoline. 130 mg (54%) of the title compound were obtained as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293913B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-33f59e59cc0c4fcd9053a40576db069e |
| Source note | uspto-grants-2012_10 |