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HRID2068148

反应详情

EQUATION

反应方程式

HRID 2068148 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N1C[C@H]2CNC[C@H]2C1
HCID1514452

tert-Butyl (3aR,6aS)-hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

C11H20N2O2

结构：O=S(=O)(c1cccc(F)c1)c1cnc2c(I)cccc2c1
HCID67314157

未命名化合物

PRODUCTS

生成物

1
结构：Cl.O=S(=O)(c1cccc(F)c1)c1cnc2c(N3C[C@H]4CNC[C@H]4C3)cccc2c1
HCID68727366

未命名化合物

PROCEDURE

实验过程

0.145 g of 3-(3-Fluoro-benzenesulfonyl)-8-(3aR,6aS)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl-quinoline hydrochloride were prepared by analogy to the methods of Examples 27 and 28 by coupling of 3-(3-fluorophenylsulfonyl)-8-iodoquinoline with commercially available (3aR,6aS)-Hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester and subsequent deprotection of the tert-butyl-oxycarbonyl derivative with HCl in isoproanol.