HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Acetate → 5-(4-(3,5-Dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)pentyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Acetate | HCID 517044 | — |
| Reactant | 8-(5-Bromopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one | HCID 24849569 | — |
| Product | 5-(4-(3,5-Dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)pentyl acetate | HCID 24849842 | — |
Reaction Steps
The title compound can be prepared from potassium acetate and 8-(5-bromopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one (Example 28) following the procedure outlined in Example 52. 1H NMR (400 MHz, DMSO-d6): δ 9.53 (s, 1H), 8.83 (s, 2H), 7.95 (d, 1H), 7.22 (s, 1H), 4.65 (s, 1H), 4.00 (m, 4H), 3.93 (s, 3H), 2.00 (s, 3H), 1.73-1.52 (m, 6H); MS (ESI): 480.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745646B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-96a3f357d5df46898e1d9cfde2fd8986 |
| Source note | uspto-grants-2010_06 |