反应详情

[4-(4-Chloro-1,2-diphenyl-but-1-enyl)-phenoxy]-acetic acid ethyl ester (Example 7) was dissolved in tetrahydrofuran at room temperature under nitrogen atmosphere. Lithium aluminium hydride was added to the solution in small portions until the reaction was complete. The reaction was quenched by adding saturated ammonium chloride solution to the mixture. The product was extracted into toluene, which was dried and evaporated in vacuo. The yield 100 mg, 43%.

1. customThe reaction was quenched
2. additionby adding saturated ammonium chloride solution to the mixture
3. extractionThe product was extracted into toluene, which
4. customwas dried
5. customevaporated in vacuo