HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 178499524, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Methyl 4-oxo-3-(pyridin-2-ylcarbonyl)pentanoate | HCID 67005342 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178499524 | HCID 178499524 | — |
Reaction Steps
1.170 g (23 mmol) of hydrazine hydrate were added to a solution of 5 g (21 mmol) of methyl 4-oxo-3-(pyridin-2-ylcarbonyl)pentanoate in ethanol (50 ml). The mixture was heated at reflux for 7 hours, added to water and extracted with ethyl acetate. The combined organic phases were dried with magnesium sulfate, filtrered and concentrated. This gave 2.290 g of product (41.9% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08298994B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-737ccd0aee6e489da43cd6a6f7f61b86 |
| Source note | uspto-grants-2012_10 |