Trifluoroacetic acid → HCID 59238162, compound

Participants

Reaction Steps

4-(1-tert-butoxycarbonylmethyl-1H-indol-5-yl)-piperazine-1-carboxylic acid tert-butyl ester (8.80 g) was treated with a mixture of 60 mL of TFA in 120 mL of methylene chloride overnight at room temperature. At this time, the solvent was removed in vacuo. This resulted in 11.26 g of a light yellow residue. This residue was used without further purification in the next step.

Provenance & Evidence