Sodium Hydroxide → HCID 178518705, compound

Participants

Reaction Conditions

Reaction Steps

An aqueous NaOH solution (2 equiv.) was added to a solution of 4,6-dichloro-3,5-dihydro-imidazo[4,5-c]pyridine in water. The reaction mixture was stirred at 90° C. until the completion of the reaction (monitored by TLC). The reaction mixture was allowed to cool down to room temperature and filtered to give light yellow residue. The residue was dissolved in water and acidified to pH 3-4 and was filtered to give 2.

Provenance & Evidence