Trifluoroacetic acid → HCID 67211910, compound

Participants

Reaction Steps

4-(3-ethoxycarbonylmethyl-4-oxo-4,5-dihydro-3H-imidazo[4,5-c]pyridin-6-yl)-piperazine-1-carboxylic acid tert-butyl ester, 4 was dissolved in dry methylene chloride at room temperature under N2. CF3COOH (5 equiv.) was added, and the reaction mixture was stirred for 1.5 h. Then methylene chloride was removed in vacuo and the residue was used in the next step without further purification.

Provenance & Evidence