HCID 59238209, compound → HCID 59238190, compound

Participants

Reaction Steps

To a solution of 1.47 g of (6-chloro-2-piperazin-1-yl-purin-7-yl)-acetic acid ethyl ester, 5 in 100 mL of methanol, was added 400 mg of 10% Pt/C and 1.1 g MgO under N2, then the reaction was hydrogenated for 4 h. The catalyst and MgO were filtered and washed with methanol. Evaporation of the methanol in vacuo gave 6.

Provenance & Evidence