反应详情

Benzyl alcohol (0.25 mL; Ald), triphenylphosphine (1.29 g), and TMAD (850 mg; Ald) were added to a toluene (30 mL) solution of Intermediate 7 (500 mg) and the resulting mixture was stirred at room temperature for 13 hours. The reaction mixture solution was filtrated, the solvent was evaporated under reduced pressure, and the residue was purified by column chromatography (Yamazen; n-hexane/ethyl acetate) to give the title compound (186 mg).

1. filtrationThe reaction mixture solution was filtrated
2. customthe solvent was evaporated under reduced pressure
3. customthe residue was purified by column chromatography (Yamazen; n-hexane/ethyl acetate)