4-Methoxybenzylamine → HCID 11561137, compound

HRID 2069213Notes

Reaction equation

HRID 2069213 reaction equation
F[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]2=[O:21].[CH3:22][O:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH2:29])=[CH:26][CH:25]=1>>[CH3:22][O:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH:29][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][C:11]=2[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]3=[O:21])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 754524-MethoxybenzylamineHCID 58964482N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide

Product 1

HCID 11561137HCID 11561137, compoundYield 60%

Procedure

N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (30 mg, 0.0943 mmol) is reacted with 4-methoxy-benzylamine according to the GPA affording 24.7 mg (60%) of a red powder. Rt=4.97 min.

Sources & evidence

ORD record
ord-cfc2504ec8684beb9b4c7774f7c86e45
Source dataset
uspto-grants-2012_10
Patent number
US08299085B2

Reaction notes

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