2-Methylimidazole → HCID 11682363, compound

HRID 2069215Notes

Reaction equation

HRID 2069215 reaction equation
F[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]2=[O:21].[CH3:22][C:23]1[NH:24][CH:25]=[CH:26][N:27]=1>>[CH3:22][C:23]1[N:24]([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][C:11]=2[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]3=[O:21])[CH:25]=[CH:26][N:27]=1

Participants

3

Reactant 2

HCID 127492-MethylimidazoleHCID 58964482N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide

Product 1

HCID 11682363HCID 11682363, compoundYield 49%

Procedure

N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (25 mg, 0.0786 mmol) is reacted with 2-methyl-1H-imidazole according to the GPA affording 14.5 mg (49%) of a yellowish powder. Rt=1.98 min.

Sources & evidence

ORD record
ord-fb0308e3abcc47a0b30983a74298542f
Source dataset
uspto-grants-2012_10
Patent number
US08299085B2

Reaction notes

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