反应详情

300 mg of 2-nitro-5-thiomorpholin-4-yl-4-trifluoromethyl-benzoic acid methyl ester in 10 ml of dry ethanol are hydrogenated in presence of 60 mg of Raney nickel, After filtration of the catalyst the solution is evaporated to dryness yielding 233 mg of 2-amino-5-thiomorpholin-4-yl-4-trifluoromethyl-benzoic acid methyl ester as yellow powder, m.p. 85-117° C. (decomp.).

1. filtrationAfter filtration of the catalyst the solution
2. customis evaporated to dryness