反应详情

In a similar way a solution of 5-(4-trifluoromethyl-imidazol-1-yl)-2-nitro-4-trifluoromethyl-benzoic acid methyl ester (1.0 g, 2.6 mmol) in 100 ml methanol is hydrogenated over 55 mg of 10% palladium on charcoal to obtain after the usual workup procedure 840 mg (2.38 mmol, 91%) of amorphous 2-amino-5-(4-trifluoromethyl-imidazol-1 -yl)-4-trifluoromethyl-benzoic acid methyl ester, ES-MS: m/z 354 [M+H]+.