HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2069319Generated: October 26, 2026
Hydrazine hydrate (1:1) → 4-(3-Dimethylaminopyrrolidin-1-yl)benzohydrazide
https://huagongshe.com/reaction/2069319
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Ethyl 4-(3-dimethylaminopyrrolidin-1-yl)benzoate | HCID 69209289 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(3-Dimethylaminopyrrolidin-1-yl)benzohydrazide | HCID 69213108 | — |
Reaction Steps
A mixture of ethyl 4-(3-dimethylaminopyrrolidin-1-yl)benzoate (2.0 g), hydrazine hydrate (3.8 g) and ethanol (7 ml) was boiled under reflux for 15 hours. After cooling to 5° C., the resulting precipitate was filtered off with suction. The product with the molecular weight of 248.33 (C13H20N4O) was obtained in this way; MS (ESI): 249 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08299104B2 |
|---|
| Source dataset | uspto-grants-2012_10 |
|---|
| ORD ID | ord-5a516f4aadef42b6a42ec5bb47a12261 |
|---|
| Source note | uspto-grants-2012_10 |
|---|
