反应详情

温度

5 °C

A mixture of ethyl 4-(3-dimethylaminopyrrolidin-1-yl)benzoate (2.0 g), hydrazine hydrate (3.8 g) and ethanol (7 ml) was boiled under reflux for 15 hours. After cooling to 5° C., the resulting precipitate was filtered off with suction. The product with the molecular weight of 248.33 (C13H20N4O) was obtained in this way; MS (ESI): 249 (M+H+).

1. temperatureunder reflux for 15 hours
2. filtrationthe resulting precipitate was filtered off with suction
3. customThe product with the molecular weight of 248.33 (C13H20N4O) was obtained in this way