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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2069321Generated: October 25, 2026

2-[(2-Phenoxyethyl)Thio]Acetic Acid → Dimethyl-(1-{4-[5-(2-phenoxyethylsulfanylmethyl)-[1,3,4]oxadiazol-2-yl]phenyl}pyrrolidin-3-yl)amine

https://huagongshe.com/reaction/2069321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(2-Phenoxyethyl)Thio]Acetic AcidHCID 2779087—
Reactant4-(3-Dimethylaminopyrrolidin-1-yl)benzohydrazideHCID 69213108—
ProductDimethyl-(1-{4-[5-(2-phenoxyethylsulfanylmethyl)-[1,3,4]oxadiazol-2-yl]phenyl}pyrrolidin-3-yl)amineHCID 11495554—

Reaction Steps

4-(3-Dimethylaminopyrrolidin-1-yl)benzohydrazide was reacted with (2-phenoxy-ethylsulfanyl)acetic acid by Method A. The product with the molecular weight of 424.57 (C23H28N4O2S) was obtained in this way; MS (ESI): 425 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08299104B2
Source datasetuspto-grants-2012_10
ORD IDord-a240b8acab8b441b8d0c75e7fe358d92
Source noteuspto-grants-2012_10