反应详情

From L-valine ethyl ester (1.0 g, 6.9 mmol), dichloromethane (1 ml) and cis-1,4-dichloro-2-butene (250 mg, 2.0 mmol). Flash chromatography: silica gel, gradient neat hexane to hexane:ethyl acetate (1:2) afforded the product (205 mg, 52%) as yellow oil.