HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 11229997, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | L-Phenylalanine, methyl ester | HCID 736234 | — |
| Reactant | 1,4-Dichloro-cis-2-butene | HCID 6432115 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | HCID 11229997 | HCID 11229997 | 62% |
Reaction Steps
From L-phenylalanine methyl ester (365 mg, 2.04 mmol), dichloromethane (4 ml) and cis-1,4-dichloro-2-butene (71 mg, 0.58 mmol). Flash chromatography: silica gel, hexane:ethyl acetate (2:1) afforded the product (83 mg, 62%) as colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299113B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-4adb9a963d3a482db071ab9d474374de |
| Source note | uspto-grants-2012_10 |